1.Variation of extracellular proteases produced by Vibrio vulnificus clinical isolates: Genetic diversity of the metalloprotease gene (vvp), and serine protease secretion by vvp-negative strains. 2.An extracellular serine protease produced by Vibrio vulnificus NCIMB 2137, a metalloprotease-gene negative strain isolated from a diseased eel. 3.Targeting neddylation pathway with MLN4924(Pevonedistat) induce NOXA-dependent apoptosis in renal cell carcinoma. |